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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 14.55
Human Site: S1028 Identified Species: 21.33
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 S1028 V P P K P K P S R V K E K F L
Chimpanzee Pan troglodytes XP_518055 1227 139177 S1021 I P P K P K P S R V K E K F L
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S1028 V P P K P K P S R V K E K F L
Dog Lupus familis XP_549061 1234 139874 S1030 I P P K P K P S R F K E K F L
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 C1030 I P P K P K P C R I K E K C L
Rat Rattus norvegicus Q7M6Z5 1394 158861 L1180 H E Q K M Q L L L H H F K D Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S1022 V S P E S P D S P F D Y I P P
Frog Xenopus laevis Q91784 1226 138905 F1030 S P D S P F D F I P P K P R G
Zebra Danio Brachydanio rerio Q58G59 1363 154819 A1133 R R L Q M A L A E L E L R V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 L591 P I E V K Q R L Y T Q A K Y D
Honey Bee Apis mellifera XP_395595 1064 123475 E871 Y Y V K Q K K E C M S K Q L V
Nematode Worm Caenorhab. elegans P46873 699 78760 K506 S Q L E K E V K K S K G Y E R
Sea Urchin Strong. purpuratus P46872 699 78679 M506 A L E M K E R M A K Q E S M R
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 N851 F T N R G R W N Q L R S M G D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 L842 N R G R W N Q L R S M G E A K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 Q735 N G K T V Q Q Q L A E F D V M
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 93.3 100 86.6 N.A. 73.3 13.3 N.A. N.A. 20 13.3 0 N.A. 6.6 13.3 6.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 20 N.A. N.A. 26.6 20 33.3 N.A. 26.6 40 26.6 20
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 0 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 40 N.A. N.A. 20 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 7 0 7 7 7 0 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 7 7 0 0 0 0 7 0 % C
% Asp: 0 0 7 0 0 0 13 0 0 0 7 0 7 7 13 % D
% Glu: 0 7 13 13 0 13 0 7 7 0 13 38 7 7 7 % E
% Phe: 7 0 0 0 0 7 0 7 0 13 0 13 0 25 0 % F
% Gly: 0 7 7 0 7 0 0 0 0 0 0 13 0 7 7 % G
% His: 7 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % H
% Ile: 19 7 0 0 0 0 0 0 7 7 0 0 7 0 0 % I
% Lys: 0 0 7 44 19 38 7 7 7 7 38 13 44 0 7 % K
% Leu: 0 7 13 0 0 0 13 19 13 13 0 7 0 7 32 % L
% Met: 0 0 0 7 13 0 0 7 0 7 7 0 7 7 7 % M
% Asn: 13 0 7 0 0 7 0 7 0 0 0 0 0 0 0 % N
% Pro: 7 38 38 0 38 7 32 0 7 7 7 0 7 7 7 % P
% Gln: 0 7 7 7 7 19 13 7 7 0 13 0 7 0 7 % Q
% Arg: 7 13 0 13 0 7 13 0 38 0 7 0 7 7 13 % R
% Ser: 13 7 0 7 7 0 0 32 0 13 7 7 7 0 0 % S
% Thr: 0 7 0 7 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 19 0 7 7 7 0 7 0 0 19 0 0 0 13 7 % V
% Trp: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 0 0 0 0 7 0 0 7 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _